The desire for simplicity in the complexity of living systems

Complexity is one of the key features of biological living systems and it is a matter of fact that some questions cannot be answered with the traditional most popular genetic model systems. Moreover, high throughput genomics and proteomics approaches are producing an incredibly huge amount of biomedical data. The development and study of new atypical model organisms and the generation of mathematical and computational models are now a necessity and are starting to be used to accelerate the process of knowledge discovery of biological systems.